FHIR Standards

Profiles Used

Resource	Profile URL
DiagnosticReport	http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomics-report
Observation (Laboratory)	http://terminology.hl7.org/CodeSystem/observation-category
Observation (Genetics)	http://terminology.hl7.org/CodeSystem/v2-0074
Variant	http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant

Standard Terminologies

LOINC Codes (Sputum & Genomics)

Code	Display Name	Usage
69548-6	Genetic variant assessment	Observation (Variant)
89486-5	Mycobacterial susceptibility panel	Observation (Panel)
81247-9	Master HL7 genetic variant reporting panel	DiagnosticReport
SP000800	Deeplex Myc-TB codon change	Variant Component
48005-3	Amino acid change (pHGVS)	Variant Component
48018-6	Gene studied [ID]	Variant Component
53037-8	Genetic variation clinical significance [Imp]	Variant Component (WHO Class)
614-8	Mycobacterial strain [Type]	Lineage Observation

LOINC Codes (Drug Susceptibility)

Used within the Susceptibility Panel Observation.

Code	Display Name
89489-9	Rifampin [Susceptibility] by Genotype method
89488-1	Isoniazid [Susceptibility] by Genotype method
92242-7	Pyrazinamide [Susceptibility] by Genotype method
89491-5	Ethambutol [Susceptibility] by Genotype method
96112-8	Moxifloxacin [Susceptibility] by Genotype method
20629-2	levoFLOXacin [Susceptibility]
96107-8	Bedaquiline [Susceptibility] by Genotype method
96111-0	Linezolid [Susceptibility] by Genotype method
96114-4	Streptomycin [Susceptibility] by Genotype method
89484-0	Amikacin [Susceptibility] by Genotype method

WHO Classification

Code	Display Name	Usage
LA26333-7	http://loinc.org	Uncertain significance
SP000478	http://terminology.kemkes.go.id/sp	Assoc w R
SP000479	http://terminology.kemkes.go.id/sp	Assoc w R - Interim
SP000481	http://terminology.kemkes.go.id/sp	Not assoc w R
SP000480	http://terminology.kemkes.go.id/sp	Not assoc w R - Interim

Clinical Conclusion Codes

Used in DiagnosticReport.conclusionCode.

Diagnosis	Code	System
Sensitive	TB-SO	https://terminology.kemkes.go.id/CodeSystem/episodeofcare-type
RR-TB	415345001	http://snomed.info/sct
HR-TB	414546009	http://snomed.info/sct
MDR-TB	423092005	http://snomed.info/sct
Pre-XDR-TB	OV000435	http://terminology.kemkes.go.id/CodeSystem/clinical-term
XDR-TB	710106005	http://snomed.info/sct
Streptomycin mono-resistant	415622003	http://snomed.info/sct
Ethionamide mono-resistant	414149006	http://snomed.info/sct
Pyrazinamide mono-resistant	415222009	http://snomed.info/sct
Ciprofloxacin mono-resistant	413852006	http://snomed.info/sct
Ethambutol mono-resistant	414146004	http://snomed.info/sct
Drug-resistant (Other)	413556004	http://snomed.info/sct